The rapid decline in synthesis and sequencing costs coupled with advances in reporter assay experimentation have enabled the examination of thousands or millions of sequences in a single experiment. Many types of high throughput reporter assay experiments exist, with most widespread being massively parallel reporter assays (MPRAs) and self-transcribing active regulatory region sequencing (STARR-seq).

The recent popularity of these methods has resulted in hundreds of research articles accompanied by the experimental datasets. We have generated MPRAbase, a database in which we have gathered these experiments, processed them and presented them in a user-friendly manner.